They will make war against the Lamb, but the Lamb will overcome them because he is Lord of lords and King of kings - and with him will be his called, chosen and faithful followers." (Revelation 17:14)
The above is a prophecy regarding a future war between the Antichrist and his allies against Jesus. As John writes victory is sure because Jesus is Lord of Lords and King of Kings.
Jesus is always the victor.
Satan thought he was winning a great victory when he got some men inspired by him to crucify Jesus. Alas, that was his greatest mistake.
The Bible says,
And having disarmed the powers and authorities, he made a public spectacle of them, triumphing over them by the cross. (Colossians 2:15)
When satan thought Jesus was losing while being crucified, he himself actually was being crushed. The prophecy of Genesis Ch.3 was being fulfilled.
And I will put enmity between you and the woman, and between your offspring and hers; he will crush your head, and you will strike his heel." (Genesis 3:15)
Regarding the Antichrist who will be satan's chief weapon in the Tribulation period, the Bible says,
And then the lawless one will be revealed, whom the Lord Jesus will overthrow with the breath of his mouth and destroy by the splendor of his coming. (2 Thessalonians 2:8)
Finally will come the doom of satan as is outlined in Revelation Ch. 20.
And the devil, who deceived them, was thrown into the lake of burning sulfur, where the beast and the false prophet had been thrown. They will be tormented day and night for ever and ever. (Revelation 20:10)
Praise God. Jesus is always the victor, now and forever. If you are a believer, here's a promise for you from Jesus himself:
To him who overcomes, I will give the right to sit with me on my throne, just as I overcame and sat down with my Father on his throne. (Revelation 3:21)